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Adolescent exposure for the Spice/K2 cannabinoid JWH-018 impairs sensorimotor gating and alters cortical perineuronal nets in the intercourse-dependent manner

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JWH 018 can be a artificial cannabinoid found in many versions in the herbal mixture Spice. Illicit use of this artificial cannabinoid centers on its psychoactive steps

JWH-018 is revealed to result in profound variations in CB1 receptor density next administration, causing desensitization to its outcomes extra speedily than associated cannabinoids.

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